PROLIFERATION IS A CENTRAL INDEPENDENT PROGNOSTIC FACTOR AND TARGET FOR PERSONALIZED AND RISK-ADAPTED TREATMENT IN MULTIPLE MYELOMA

Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma

Background Proliferation of malignant plasma cells is a strong adverse prognostic factor in multiple myeloma and simultaneously targetable by available (e.g.tubulin polymerase inhibitors) and upcoming (e.g.aurora kinase inhibitors) compounds.Design and Methods We assessed proliferation using gene expression-based indices in 757 samples including in

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Meat productivity and quality of meat and liver of broiler chickens after consuming diet with mineral supplements containing chelates of cuprum, iron, zinc, and manganese

Poultry farming plays an important role as a producer of high-quality animal protein, which can solve issues of protein deficit among the population.Genetic growth potential of broiler chickens can be maximized through regular supply of microelements, especially chelate aminoacids.Those compounds improve metabolic processes in the body and increase

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